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Gene: NFX1 (nuclear transcription factor, X-box binding 1) Homo sapiens
Symbol: NFX1
Name: nuclear transcription factor, X-box binding 1
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to the cytosol; nuclear lumen; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp779G2416; MGC20369; NFX2; nuclear transcription factor, X box-binding protein 1; TEG-42; Tex42; transcriptional repressor NF-X1
Mus musculus (house mouse) : Nfx1 (nuclear transcription factor, X-box binding 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfx1 (nuclear transcription factor, X-box binding 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfx1 (nuclear transcription factor, X-box binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFX1 (nuclear transcription factor, X-box binding 1)
Canis lupus familiaris (dog) : NFX1 (nuclear transcription factor, X-box binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfx1 (nuclear transcription factor, X-box binding 1)
Sus scrofa (pig) : NFX1 (nuclear transcription factor, X-box binding 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl933,290,512 - 33,371,157 (+)Ensembl
GRCh38933,290,475 - 33,371,157 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37933,290,418 - 33,371,155 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,280,510 - 33,361,155 (+)NCBINCBI36hg18NCBI36
Build 34933,280,509 - 33,338,719NCBI
Celera933,220,555 - 33,301,274 (+)NCBI
Cytogenetic Map9p13.3NCBI
HuRef933,247,318 - 33,327,704 (+)NCBIHuRef
CHM1_1933,290,191 - 33,370,954 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NFX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321083
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.