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Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Mus musculus
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Symbol: Nfx1
Name: nuclear transcription factor, X-box binding 1
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of MHC class II biosynthetic process and negative regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol; nuclear lumen; and plasma membrane. Is expressed in several structures, including gut; hemolymphoid system gland; integumental system; male reproductive system; and urinary system. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300017N15Rik; 3000003M19Rik; m-Nfx.1; NFX.1; nuclear transcription factor, X box-binding protein 1; nuclear X box binding factor 1; TEG-42; testis expressed gene 42; Tex42; transcriptional repressor NF-X1
Orthologs:
Homo sapiens (human) : NFX1 (nuclear transcription factor, X-box binding 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfx1 (nuclear transcription factor, X-box binding 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfx1 (nuclear transcription factor, X-box binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFX1 (nuclear transcription factor, X-box binding 1)
Canis lupus familiaris (dog) : NFX1 (nuclear transcription factor, X-box binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfx1 (nuclear transcription factor, X-box binding 1)
Sus scrofa (pig) : NFX1 (nuclear transcription factor, X-box binding 1)
Chlorocebus sabaeus (green monkey) : NFX1 (nuclear transcription factor, X-box binding 1)
Heterocephalus glaber (naked mole-rat) : Nfx1 (nuclear transcription factor, X-box binding 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl440,970,906 - 41,025,993 (+)Ensembl
GRCm38440,970,906 - 41,025,992 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37440,917,976 - 40,973,025 (+)NCBIGRCm37mm9NCBIm37
MGSCv36441,159,652 - 41,213,849 (+)NCBImm8
Celera440,631,672 - 40,686,644 (+)NCBICelera
Cytogenetic Map4 A5NCBI
cM Map420.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nfx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321084
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.