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Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Mus musculus
Symbol: Nfx1
Name: nuclear transcription factor, X-box binding 1
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in negative regulation of MHC class II biosynthetic process and negative regulation of transcription by RNA polymerase II. Predicted to localize to the cytosol; nuclear lumen; and plasma membrane. Is expressed in several structures, including gut; hemolymphoid system gland; integumental system; male reproductive system; and urinary system. Orthologous to human NFX1 (nuclear transcription factor, X-box binding 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1300017N15Rik; 3000003M19Rik; m-Nfx.1; NFX.1; nuclear transcription factor, X box-binding protein 1; nuclear X box binding factor 1; TEG-42; testis expressed gene 42; Tex42; transcriptional repressor NF-X1
Homo sapiens (human) : NFX1 (nuclear transcription factor, X-box binding 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nfx1 (nuclear transcription factor, X-box binding 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfx1 (nuclear transcription factor, X-box binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NFX1 (nuclear transcription factor, X-box binding 1)
Canis lupus familiaris (dog) : NFX1 (nuclear transcription factor, X-box binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfx1 (nuclear transcription factor, X-box binding 1)
Sus scrofa (pig) : NFX1 (nuclear transcription factor, X-box binding 1)
Chlorocebus sabaeus (green monkey) : NFX1 (nuclear transcription factor, X-box binding 1)
Heterocephalus glaber (naked mole-rat) : Nfx1 (nuclear transcription factor, X-box binding 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl440,970,906 - 41,025,993 (+)Ensembl
GRCm38440,970,906 - 41,025,992 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37440,917,976 - 40,973,025 (+)NCBIGRCm37mm9NCBIm37
MGSCv36441,159,652 - 41,213,849 (+)NCBImm8
Celera440,631,672 - 40,686,644 (+)NCBICelera
Cytogenetic Map4 A5NCBI
cM Map420.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Nfx1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321084
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.