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Gene: PSD4 (pleckstrin and Sec7 domain containing 4) Homo sapiens
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Symbol: PSD4
Name: pleckstrin and Sec7 domain containing 4
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity and phospholipid binding activity. Predicted to be involved in regulation of ARF protein signal transduction. Localizes to ruffle membrane; PARTICIPATES IN endocytosis pathway; INTERACTS WITH 17beta-estradiol; aflatoxin B1; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADP-ribosylation factor guanine nucleotide-exchange factor 6; EFA6B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; exchange factor for ARF6 B; FLJ36237; FLJ37279; PH and SEC7 domain-containing protein 4; pleckstrin homology and SEC7 domain-containing protein 4; SEC7 homolog; telomeric of interleukin-1 cluster protein; TIC
Orthologs:
Mus musculus (house mouse) : Psd4 (pleckstrin and Sec7 domain containing 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Psd4 (pleckstrin and Sec7 domain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psd4 (pleckstrin and Sec7 domain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PSD4 (pleckstrin and Sec7 domain containing 4)
Canis lupus familiaris (dog) : PSD4 (pleckstrin and Sec7 domain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psd4 (pleckstrin and Sec7 domain containing 4)
Chlorocebus sabaeus (African green monkey) : PSD4 (pleckstrin and Sec7 domain containing 4)
Heterocephalus glaber (naked mole-rat) : Psd4 (pleckstrin and Sec7 domain containing 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2113,157,325 - 113,209,396 (+)EnsemblGRCh38hg38GRCh38
GRCh382113,157,399 - 113,209,391 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,914,976 - 113,960,677 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,648,031 - 113,677,148 (+)NCBINCBI36hg18NCBI36
Build 342113,647,790 - 113,676,908NCBI
Celera2107,316,145 - 107,345,262 (+)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,385,554 - 106,414,668 (+)NCBIHuRef
CHM1_12113,935,985 - 113,965,077 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on PSD4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321104
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.