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Gene: Cyfip1 (cytoplasmic FMR1 interacting protein 1) Mus musculus
Symbol: Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Description: Exhibits translation regulator activity. Predicted to contribute to Rac GTPase binding activity. Involved in several processes, including dendrite extension; positive regulation of neurotrophin TRK receptor signaling pathway; and regulation of modification of postsynaptic actin cytoskeleton. Localizes to several cellular components, including lamellipodium; mRNA cap binding activity complex; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Is expressed in several structures, including embryo mesenchyme; lung; nervous system; skeletal muscle; and tooth. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cytoplasmic FMR1-interacting protein 1; E030028J09Rik; KIAA0068; l(7)1Rl; l71Rl; l7Rl1; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; specifically Rac1-associated protein 1; Sra-1; Sra1
Homo sapiens (human) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Canis lupus familiaris (dog) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)
Sus scrofa (pig) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Chlorocebus sabaeus (African green monkey) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Heterocephalus glaber (naked mole-rat) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl755,841,745 - 55,932,602 (+)EnsemblGRCm38mm10GRCm38
GRCm38755,842,022 - 55,932,633 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37763,097,441 - 63,188,003 (+)NCBIGRCm37mm9NCBIm37
MGSCv36755,739,875 - 55,798,505 (+)NCBImm8
Celera753,195,732 - 53,286,248 (+)NCBICelera
Cytogenetic Map7B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cyfip1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321176
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.