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Gene: Cyfip1 (cytoplasmic FMR1 interacting protein 1) Mus musculus
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Symbol: Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Description: Exhibits translation regulator activity. Predicted to contribute to Rac GTPase binding activity. Involved in several processes, including dendrite extension; positive regulation of neurotrophin TRK receptor signaling pathway; and regulation of modification of postsynaptic actin cytoskeleton. Localizes to several cellular components, including lamellipodium; mRNA cap binding activity complex; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Is expressed in several structures, including embryo mesenchyme; lung; nervous system; skeletal muscle; and tooth. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cytoplasmic FMR1-interacting protein 1; E030028J09Rik; KIAA0068; l(7)1Rl; l71Rl; l7Rl1; mKIAA0068; P140SRA-1; P140sra1; pl-1; Shyc; specifically Rac1-associated protein 1; Sra-1; Sra1
Orthologs:
Homo sapiens (human) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Canis lupus familiaris (dog) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)
Sus scrofa (pig) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Chlorocebus sabaeus (African green monkey) : CYFIP1 (cytoplasmic FMR1 interacting protein 1)
Heterocephalus glaber (naked mole-rat) : Cyfip1 (cytoplasmic FMR1 interacting protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl755,841,745 - 55,932,602 (+)EnsemblGRCm38mm10GRCm38
GRCm38755,842,022 - 55,932,633 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37763,097,441 - 63,188,003 (+)NCBIGRCm37mm9NCBIm37
MGSCv36755,739,875 - 55,798,505 (+)NCBImm8
Celera753,195,732 - 53,286,248 (+)NCBICelera
Cytogenetic Map7B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyfip1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321176
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.