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Gene: ITGA3 (integrin subunit alpha 3) Homo sapiens
Symbol: ITGA3
Name: integrin subunit alpha 3
Description: Exhibits protease binding activity and protein heterodimerization activity. Involved in several processes, including animal organ development; positive regulation of protein localization to plasma membrane; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to the cell projection membrane; cell surface; and integrin alpha3-beta1 complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49C; FLJ34631; FLJ34704; FRP-2; galactoprotein B3; GAP-B3; GAPB3; ILNEB; integrin alpha 3; integrin alpha-3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); MSK18; testicular tissue protein Li 96; testicular tissue protein Li 98; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VL3A; VLA-3 subunit alpha; VLA3a
Mus musculus (house mouse) : Itga3 (integrin alpha 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itga3 (integrin subunit alpha 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga3 (integrin subunit alpha 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA3 (integrin subunit alpha 3)
Canis lupus familiaris (dog) : ITGA3 (integrin subunit alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga3 (integrin subunit alpha 3)
Sus scrofa (pig) : ITGA3 (integrin subunit alpha 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381750,056,065 - 50,090,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371748,133,340 - 48,167,849 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,488,730 - 45,522,843 (+)NCBINCBI36hg18NCBI36
Build 341745,488,729 - 45,522,843NCBI
Celera1744,591,582 - 44,627,962 (+)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1743,500,496 - 43,535,731 (+)NCBIHuRef
CHM1_11748,197,206 - 48,232,155 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ITGA3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321177
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.