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Gene: CENPJ (centromere protein J) Homo sapiens
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Symbol: CENPJ
Name: centromere protein J
Description: Exhibits several functions, including identical protein binding activity; protein kinase binding activity; and tubulin binding activity. Involved in microtubule cytoskeleton organization; positive regulation of centriole elongation; and positive regulation of establishment of protein localization. Localizes to the microtubule organizing center; nucleoplasm; and plasma membrane. Implicated in Seckel syndrome 4; primary autosomal recessive microcephaly; and primary autosomal recessive microcephaly 6.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BM032; CENP-J; centrosomal P4.1-associated protein; CPAP; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; LYST-interacting protein LIP1; LYST-interacting protein LIP7; MCPH6; MGC131581; MGC131582; MGC142222; MGC142224; microcephaly, primary autosomal recessive 6; Sas-4; SASS4; SCKL4; Spindle assembly abnormal 4
Orthologs:
Mus musculus (house mouse) : Cenpj (centromere protein J)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cenpj (centromere protein J)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cenpj (centromere protein J)
Pan paniscus (bonobo/pygmy chimpanzee) : CENPJ (centromere protein J)
Canis lupus familiaris (dog) : CENPJ (centromere protein J)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cenpj (centromere protein J)
Sus scrofa (pig) : CENPJ (centromere protein J)
Chlorocebus sabaeus (African green monkey) : CENPJ (centromere protein J)
Heterocephalus glaber (naked mole-rat) : Cenpj (centromere protein J)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1324,882,279 - 24,922,889 (-)EnsemblGRCh38hg38GRCh38
GRCh381324,882,279 - 24,922,889 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371325,456,412 - 25,497,027 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,354,412 - 24,395,085 (-)NCBINCBI36hg18NCBI36
Build 341324,355,171 - 24,395,018NCBI
Celera136,519,974 - 6,560,638 (-)NCBI
Cytogenetic Map13q12.12-q12.13NCBI
HuRef136,269,821 - 6,310,405 (-)NCBIHuRef
CHM1_11325,425,035 - 25,465,641 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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RNA-SEQ Expression

Sequence

Nucleotide Sequences
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Additional Information

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Nomenclature History
 
More on CENPJ
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321379
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.