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Gene: CHD6 (chromodomain helicase DNA binding protein 6) Homo sapiens
Symbol: CHD6
Name: chromodomain helicase DNA binding protein 6
Description: Exhibits DNA-dependent ATPase activity and transcription cofactor binding activity. Involved in positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress. Localizes to nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent helicase CHD6; CHD-6; CHD5; chromodomain-helicase-DNA-binding protein 6; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein; KIAA1335; radiation-induced gene B protein; RIGB
Mus musculus (house mouse) : Chd6 (chromodomain helicase DNA binding protein 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chd6 (chromodomain helicase DNA binding protein 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chd6 (chromodomain helicase DNA binding protein 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CHD6 (chromodomain helicase DNA binding protein 6)
Canis lupus familiaris (dog) : CHD6 (chromodomain helicase DNA binding protein 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chd6 (chromodomain helicase DNA binding protein 6)
Sus scrofa (pig) : CHD6 (chromodomain helicase DNA binding protein 6)
Chlorocebus sabaeus (African green monkey) : CHD6 (chromodomain helicase DNA binding protein 6)
Heterocephalus glaber (naked mole-rat) : Chd6 (chromodomain helicase DNA binding protein 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2041,402,083 - 41,618,384 (-)EnsemblGRCh38hg38GRCh38
GRCh382041,402,083 - 41,618,377 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372040,030,741 - 40,247,133 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,464,584 - 39,680,547 (-)NCBINCBI36hg18NCBI36
Build 342039,464,583 - 39,680,547NCBI
Celera2036,741,838 - 36,957,790 (-)NCBI
Cytogenetic Map20q12NCBI
HuRef2036,768,458 - 36,984,731 (-)NCBIHuRef
CHM1_12039,935,021 - 40,151,300 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CHD6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321381
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.