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Gene: Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1) Mus musculus
Symbol: Hoga1
Name: 4-hydroxy-2-oxoglutarate aldolase 1
Description: Predicted to have 4-hydroxy-2-oxoglutarate aldolase activity and protein homodimerization activity. Predicted to be involved in carboxylic acid metabolic process. Localizes to mitochondrion. Used to study primary hyperoxaluria. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 3. Orthologous to human HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1); INTERACTS WITH 17beta-estradiol; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 0610010D20Rik; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; DHDPS-like protein; Dhdpsl; dihydrodipicolinate synthase-like; dihydrodipicolinate synthase-like, mitochondrial; N-acetylneuraminate pyruvate lyase 2 (putative); Npl2; probable 2-keto-4-hydroxyglutarate aldolase; probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; probable KHG-aldolase
Homo sapiens (human) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Canis lupus familiaris (dog) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)
Sus scrofa (pig) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Chlorocebus sabaeus (African green monkey) : HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)
Heterocephalus glaber (naked mole-rat) : Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1942,045,610 - 42,070,953 (+)EnsemblGRCm38mm10GRCm38
GRCm381942,045,559 - 42,071,689 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371942,120,341 - 42,145,429 (+)NCBIGRCm37mm9NCBIm37
MGSCv361942,099,162 - 42,124,250 (+)NCBImm8
Celera1942,849,723 - 42,874,820 (+)NCBICelera
Cytogenetic Map19C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hoga1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321400
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.