Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PHLDA3 (pleckstrin homology like domain family A member 3) Homo sapiens
Analyze
Symbol: PHLDA3
Name: pleckstrin homology like domain family A member 3
Description: Exhibits phosphatidylinositol phosphate binding activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of protein kinase B signaling; and positive regulation of apoptotic process. Localizes to plasma membrane; INTERACTS WITH (-)-demecolcine; (S)-colchicine; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: pleckstrin homology-like domain family A member 3; pleckstrin homology-like domain, family A, member 2; pleckstrin homology-like domain, family A, member 3; TDAG51/Ipl homolog 1; TIH1
Orthologs:
Mus musculus (house mouse) : Phlda3 (pleckstrin homology like domain, family A, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phlda3 (pleckstrin homology-like domain, family A, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phlda3 (pleckstrin homology like domain family A member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PHLDA3 (pleckstrin homology like domain family A member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phlda3 (pleckstrin homology like domain family A member 3)
Sus scrofa (pig) : PHLDA3 (pleckstrin homology like domain family A member 3)
Chlorocebus sabaeus (African green monkey) : PHLDA3 (pleckstrin homology like domain family A member 3)
Heterocephalus glaber (naked mole-rat) : Phlda3 (pleckstrin homology like domain family A member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1201,464,278 - 201,469,237 (-)EnsemblGRCh38hg38GRCh38
GRCh381201,464,278 - 201,469,188 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371201,434,607 - 201,438,299 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,701,245 - 199,704,922 (-)NCBINCBI36hg18NCBI36
Build 341198,166,279 - 198,169,956NCBI
Celera1174,558,492 - 174,562,169 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1172,600,628 - 172,604,316 (-)NCBIHuRef
CHM1_11202,855,540 - 202,860,431 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PHLDA3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321441
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.