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Gene: TGIF1 (TGFB induced factor homeobox 1) Homo sapiens
Symbol: TGIF1
Name: TGFB induced factor homeobox 1
CRRD ID: 1321463
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Localizes to nucleoplasm. Implicated in holoprosencephaly and holoprosencephaly 4.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5'-TG-3' interacting factor; 5'-TG-3'-interacting factor 1; homeobox protein TGIF; homeobox protein TGIF1; HPE4; MGC39747; MGC5066; TALE homeobox TG-interacting factor; tgfb-induced factor (tale family homeobox); TGFB-induced factor homeobox 1; TGIF; transforming growth factor-beta-induced factor
Mus musculus (house mouse) : Tgif1 (TGFB-induced factor homeobox 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tgif1 (TGFB-induced factor homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgif1 (TGFB induced factor homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TGIF1 (TGFB induced factor homeobox 1)
Canis lupus familiaris (dog) : TGIF1 (TGFB induced factor homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgif1 (TGFB induced factor homeobox 1)
Sus scrofa (pig) : TGIF1 (TGFB induced factor homeobox 1)
Chlorocebus sabaeus (African green monkey) : TGIF1 (TGFB induced factor homeobox 1)
Heterocephalus glaber (naked mole-rat) : Tgif1 (TGFB induced factor homeobox 1)
more info ...
Related Pseudogenes: TGIF1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl183,411,608 - 3,459,978 (+)EnsemblGRCh38hg38GRCh38
GRCh38183,412,009 - 3,459,978 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37183,411,925 - 3,458,409 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36183,402,072 - 3,448,409 (+)NCBINCBI36hg18NCBI36
Build 34183,402,071 - 3,448,404NCBI
Celera183,291,675 - 3,337,991 (+)NCBI
Cytogenetic Map18p11.31NCBI
HuRef183,376,674 - 3,423,225 (+)NCBIHuRef
CHM1_1183,411,321 - 3,457,803 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TGIF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321463
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.