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Gene: Tgif1 (TGFB-induced factor homeobox 1) Mus musculus
Symbol: Tgif1
Name: TGFB-induced factor homeobox 1
CRRD ID: 1321464
Description: Exhibits chromatin binding activity. Involved in several processes, including negative regulation of retinoic acid receptor signaling pathway; nervous system development; and nodal signaling pathway. Localizes to nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; embryo ectoderm; and genitourinary system. Used to study otitis media. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 4. Orthologous to human TGIF1 (TGFB induced factor homeobox 1); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 1,4-dichlorobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5'-TG-3'-interacting factor 1; AA959811; AI462167; homeobox protein TGIF1; TALE family homeobox; TG interacting factor 1; Tgi; Tgif
Homo sapiens (human) : TGIF1 (TGFB induced factor homeobox 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tgif1 (TGFB-induced factor homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgif1 (TGFB induced factor homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TGIF1 (TGFB induced factor homeobox 1)
Canis lupus familiaris (dog) : TGIF1 (TGFB induced factor homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgif1 (TGFB induced factor homeobox 1)
Sus scrofa (pig) : TGIF1 (TGFB induced factor homeobox 1)
Chlorocebus sabaeus (African green monkey) : TGIF1 (TGFB induced factor homeobox 1)
Heterocephalus glaber (naked mole-rat) : Tgif1 (TGFB induced factor homeobox 1)
more info ...
Related Pseudogenes: Tgif1-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391771,151,200 - 71,160,527 (-)NCBI
GRCm381770,844,205 - 70,853,532 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1770,844,205 - 70,853,546 (-)EnsemblGRCm38mm10GRCm38
MGSCv371771,193,545 - 71,202,872 (-)NCBIGRCm37mm9NCBIm37
MGSCv361770,749,072 - 70,756,055 (-)NCBImm8
Celera1775,106,130 - 75,115,447 (-)NCBICelera
Cytogenetic Map17E1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tgif1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321464
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.