Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SCRIB (scribble planar cell polarity protein) Homo sapiens
Symbol: SCRIB
Name: scribble planar cell polarity protein
Description: Exhibits cadherin binding activity. Involved in several processes, including activation of GTPase activity; morphogenesis of an epithelium; and positive regulation of receptor recycling. Localizes to several cellular components, including Scrib-APC-beta-catenin complex; adherens junction; and nucleoplasm. Colocalizes with cell leading edge; postsynaptic membrane; and presynaptic membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CRIB1; hScrib; protein scribble homolog; SCRB1; SCRIB1; scribble; scribbled homolog; Vartul
Mus musculus (house mouse) : Scrib (scribbled planar cell polarity)  MGI  Alliance
Rattus norvegicus (Norway rat) : Scrib (scribble planar cell polarity protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Scrib (scribble planar cell polarity protein)
Pan paniscus (bonobo/pygmy chimpanzee) : SCRIB (scribble planar cell polarity protein)
Canis lupus familiaris (dog) : SCRIB (scribble planar cell polarity protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scrib (scribble planar cell polarity protein)
Sus scrofa (pig) : SCRIB (scribble planar cell polarity protein)
Chlorocebus sabaeus (African green monkey) : SCRIB (scribble planar cell polarity protein)
Heterocephalus glaber (naked mole-rat) : Scrib (scribble planar cell polarity protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8143,790,920 - 143,815,773 (-)EnsemblGRCh38hg38GRCh38
GRCh388143,790,925 - 143,815,773 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,873,090 - 144,897,890 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,945,078 - 144,969,537 (-)NCBINCBI36hg18NCBI36
Celera8141,185,992 - 141,210,452 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,126,075 - 140,150,540 (-)NCBIHuRef
CHM1_18144,913,332 - 144,937,791 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SCRIB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321471
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.