Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: SEMA4D (semaphorin 4D) Homo sapiens
Symbol: SEMA4D
Name: semaphorin 4D
Description: Exhibits identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of cell morphogenesis; and regulation of phosphate metabolic process. Localizes to the integral component of plasma membrane; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A8; BB18; C9orf164; CD100; chromosome 9 open reading frame 164; coll-4; COLL4; FLJ33485; FLJ34282; FLJ39737; FLJ46484; GR3; M-sema-G; MGC169138; MGC169141; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; SEMAJ; semaphorin-4D
Mus musculus (house mouse) : Sema4d (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sema4d (semaphorin 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema4d (semaphorin 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA4D (semaphorin 4D)
Canis lupus familiaris (dog) : SEMA4D (semaphorin 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101975744 (semaphorin-4D)
Sus scrofa (pig) : SEMA4D (semaphorin 4D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38989,360,787 - 89,498,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37991,975,706 - 92,112,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36991,181,972 - 91,284,431 (-)NCBINCBI36hg18NCBI36
Build 34989,221,705 - 89,324,165NCBI
Celera962,560,599 - 62,677,697 (-)NCBI
Cytogenetic Map9q22.2NCBI
HuRef961,809,649 - 61,812,817 (-)NCBIHuRef
HuRef961,823,373 - 61,926,322 (-)NCBIHuRef
CHM1_1992,124,533 - 92,243,431 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SEMA4D
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321523
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.