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Gene: SEMA4D (semaphorin 4D) Homo sapiens
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Symbol: SEMA4D
Name: semaphorin 4D
Description: Exhibits identical protein binding activity; semaphorin receptor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including positive regulation of phosphatidylinositol 3-kinase signaling; regulation of cell morphogenesis; and regulation of phosphate metabolic process. Localizes to the integral component of plasma membrane; INTERACTS WITH 17beta-estradiol; 2-hydroxypropanoic acid; 2-methylcholine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A8; BB18; C9orf164; CD100; chromosome 9 open reading frame 164; coll-4; COLL4; FLJ33485; FLJ34282; FLJ39737; FLJ46484; GR3; M-sema-G; MGC169138; MGC169141; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D; SEMAJ; semaphorin-4D
Orthologs:
Mus musculus (house mouse) : Sema4d (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sema4d (semaphorin 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema4d (semaphorin 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA4D (semaphorin 4D)
Canis lupus familiaris (dog) : SEMA4D (semaphorin 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101975744 (semaphorin-4D)
Sus scrofa (pig) : SEMA4D (semaphorin 4D)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38989,360,787 - 89,498,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37991,975,706 - 92,112,906 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36991,181,972 - 91,284,431 (-)NCBINCBI36hg18NCBI36
Build 34989,221,705 - 89,324,165NCBI
Celera962,560,599 - 62,677,697 (-)NCBI
Cytogenetic Map9q22.2NCBI
HuRef961,809,649 - 61,812,817 (-)NCBIHuRef
HuRef961,823,373 - 61,926,322 (-)NCBIHuRef
CHM1_1992,124,533 - 92,243,431 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SEMA4D
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321523
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.