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Gene: Sema4d (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D) Mus musculus
Symbol: Sema4d
Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Description: Exhibits semaphorin receptor binding activity. Involved in several processes, including positive regulation of nervous system development; regulation of phosphate metabolic process; and semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis. Localizes to the extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and nasal cavity. Orthologous to human SEMA4D (semaphorin 4D); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD100; coll-4; M-sema G; sema J; Semacl2; Semaj; semaphorin H; semaphorin-4D; semaphorin-C-like 2; semaphorin-J; Semcl2
Homo sapiens (human) : SEMA4D (semaphorin 4D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sema4d (semaphorin 4D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sema4d (semaphorin 4D)
Pan paniscus (bonobo/pygmy chimpanzee) : SEMA4D (semaphorin 4D)
Canis lupus familiaris (dog) : SEMA4D (semaphorin 4D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101975744 (semaphorin-4D)
Sus scrofa (pig) : SEMA4D (semaphorin 4D)
Heterocephalus glaber (naked mole-rat) : Sema4d (semaphorin 4D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1351,685,529 - 51,793,747 (-)Ensembl
GRCm381351,701,246 - 51,793,747 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm381351,685,529 - 51,701,864 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371351,796,617 - 51,889,013 (-)NCBIGRCm37mm9NCBIm37
MGSCv361351,713,744 - 51,806,140 (-)NCBImm8
Celera1352,773,981 - 52,869,050 (-)NCBICelera
Cytogenetic Map13A5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sema4d
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321524
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.