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Gene: PLXNB1 (plexin B1) Homo sapiens
Symbol: PLXNB1
Name: plexin B1
Description: ENCODES a protein that exhibits semaphorin receptor activity; GTPase activating protein binding (ortholog); INVOLVED IN negative regulation of cell adhesion; regulation of cell shape; regulation of cytoskeleton organization; ASSOCIATED WITH Neurodevelopmental Disorders; FOUND IN integral component of plasma membrane; semaphorin receptor complex; INTERACTS WITH 2-methylcholine; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0407; MGC149167; plexin 5; plexin-B1; PLXN5; semaphorin receptor SEP; SEP
Mus musculus (house mouse) : Plxnb1 (plexin B1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plxnb1 (plexin B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plxnb1 (plexin B1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLXNB1 (plexin B1)
Canis lupus familiaris (dog) : PLXNB1 (plexin B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plxnb1 (plexin B1)
Sus scrofa (pig) : PLXNB1 (plexin B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38348,403,854 - 48,430,324 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37348,445,261 - 48,471,460 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,420,267 - 48,441,746 (-)NCBINCBI36hg18NCBI36
Build 34348,420,266 - 48,441,746NCBI
Celera348,396,031 - 48,422,232 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef348,499,564 - 48,525,765 (-)NCBIHuRef
CHM1_1348,397,545 - 48,423,744 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PLXNB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321541
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.