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Gene: CH25H (cholesterol 25-hydroxylase) Homo sapiens
Symbol: CH25H
Name: cholesterol 25-hydroxylase
Description: Predicted to have C-4 methylsterol oxidase activity and cholesterol 25-hydroxylase activity. Predicted to be involved in B cell chemotaxis; cholesterol metabolic process; and sterol biosynthetic process. Predicted to localize to the endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C25H; cholesterol 25-monooxygenase; h25OH
Mus musculus (house mouse) : Ch25h (cholesterol 25-hydroxylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ch25h (cholesterol 25-hydroxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ch25h (cholesterol 25-hydroxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : CH25H (cholesterol 25-hydroxylase)
Canis lupus familiaris (dog) : CH25H (cholesterol 25-hydroxylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ch25h (cholesterol 25-hydroxylase)
Sus scrofa (pig) : CH25H (cholesterol 25-hydroxylase)
Chlorocebus sabaeus (African green monkey) : CH25H (cholesterol 25-hydroxylase)
Heterocephalus glaber (naked mole-rat) : Ch25h (cholesterol 25-hydroxylase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1089,205,629 - 89,207,317 (-)EnsemblGRCh38hg38GRCh38
GRCh381089,205,629 - 89,207,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371090,965,694 - 90,967,071 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361090,955,674 - 90,957,051 (-)NCBINCBI36hg18NCBI36
Build 341090,955,673 - 90,957,051NCBI
Celera1084,712,523 - 84,713,900 (-)NCBI
Cytogenetic Map10q23.31NCBI
HuRef1084,600,155 - 84,601,532 (-)NCBIHuRef
CHM1_11091,247,750 - 91,249,127 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on CH25H
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321560
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.