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Gene: BOP1 (BOP1 ribosomal biogenesis factor) Homo sapiens
Symbol: BOP1
Name: BOP1 ribosomal biogenesis factor
Description: Exhibits RNA binding activity. Involved in regulation of cell cycle; regulation of signal transduction by p53 class mediator; and ribosomal large subunit biogenesis. Localizes to PeBoW complex and nucleoplasm; PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH 5-fluorouracil; afimoxifene; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: block of proliferation 1; block of proliferation 1 protein; block of proliferation 1 pseudogene; KIAA0124; ribosome biogenesis protein BOP1
Mus musculus (house mouse) : Bop1 (block of proliferation 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bop1 (BOP1 ribosomal biogenesis factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bop1 (BOP1 ribosomal biogenesis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : BOP1 (BOP1 ribosomal biogenesis factor)
Canis lupus familiaris (dog) : BOP1 (BOP1 ribosomal biogenesis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bop1 (BOP1 ribosomal biogenesis factor)
Sus scrofa (pig) : BOP1 (BOP1 ribosomal biogenesis factor)
Chlorocebus sabaeus (African green monkey) : BOP1 (BOP1 ribosomal biogenesis factor)
Heterocephalus glaber (naked mole-rat) : Bop1 (BOP1 ribosomal biogenesis factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8144,262,045 - 144,291,438 (-)EnsemblGRCh38hg38GRCh38
GRCh388144,262,045 - 144,291,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378145,486,056 - 145,515,120 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,456,864 - 145,485,928 (-)NCBINCBI36hg18NCBI36
Build 348145,456,863 - 145,485,928NCBI
Celera8141,660,871 - 141,689,893 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8140,600,632 - 140,629,634 (-)NCBIHuRef
CHM1_18145,358,001 - 145,553,302 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BOP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321585
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.