Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Aars2 (alanyl-tRNA synthetase 2, mitochondrial) Mus musculus
Symbol: Aars2
Name: alanyl-tRNA synthetase 2, mitochondrial
CRRD ID: 1321624
Description: Predicted to have anion binding activity; catalytic activity, acting on a tRNA; and tRNA binding activity. Predicted to be involved in mitochondrial alanyl-tRNA aminoacylation and tRNA modification. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 8. Orthologous to human AARS2 (alanyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN alanine metabolic pathway; lactic acidosis pathway; primary hyperoxaluria type 1 pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Aarsl; alanine--tRNA ligase; alanine--tRNA ligase, mitochondrial; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; alanyl-tRNA synthetase, mitochondrial; alanyl-tRNA synthetase-like; AlaRS; Gm89; MGC69820; probable alanyl-tRNA synthetase, mitochondrial
Homo sapiens (human) : AARS2 (alanyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aars2 (alanyl-tRNA synthetase 2, mitochondrial)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aars2 (alanyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : AARS2 (alanyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : AARS2 (alanyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aars2 (alanyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : AARS2 (alanyl-tRNA synthetase 2, mitochondrial)
Chlorocebus sabaeus (African green monkey) : AARS2 (alanyl-tRNA synthetase 2, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Aars2 (alanyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391745,817,473 - 45,831,769 (+)NCBI
GRCm381745,503,515 - 45,520,843 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1745,506,841 - 45,520,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv371745,643,790 - 45,657,792 (+)NCBIGRCm37mm9NCBIm37
MGSCv361744,970,422 - 44,984,424 (+)NCBImm8
Celera1748,939,666 - 48,953,555 (+)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Aars2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321624
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.