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Gene: Nkx2-9 (NK2 homeobox 9) Mus musculus
Symbol: Nkx2-9
Name: NK2 homeobox 9
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in axonogenesis; lung development; and negative regulation of epithelial cell proliferation. Predicted to localize to the nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesoderm; liver; and lung epithelium. Orthologous to human NKX2-8 (NK2 homeobox 8); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Drosophila NK2 transcription factor related, locus 9; homeobox protein NK-2 homolog H; homeobox protein Nkx-2.8; homeobox protein Nkx-2.9; NK2 transcription factor related, locus 9; Nkx-2.9; Nkx2-8; Nkx2.9; tinman
Homo sapiens (human) : NKX2-8 (NK2 homeobox 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nkx2-8 (NK2 homeobox 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkx2-8 (NK2 homeobox 8)
Pan paniscus (bonobo/pygmy chimpanzee) : NKX2-8 (NK2 homeobox 8)
Canis lupus familiaris (dog) : NKX2-8 (NK2 homeobox 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkx2-8 (NK2 homeobox 8)
Sus scrofa (pig) : NKX2-8 (NK2 homeobox 8)
Chlorocebus sabaeus (African green monkey) : NKX2-8 (NK2 homeobox 8)
Heterocephalus glaber (naked mole-rat) : Nkx2-8 (NK2 homeobox 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1256,611,389 - 56,613,284 (-)EnsemblGRCm38mm10GRCm38
GRCm381256,611,389 - 56,613,569 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371257,712,380 - 57,714,271 (-)NCBIGRCm37mm9NCBIm37
MGSCv361257,529,411 - 57,531,296 (-)NCBImm8
Celera1257,768,666 - 57,770,465 (-)NCBICelera
Cytogenetic Map12 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Nkx2-9
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321644
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.