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Gene: CASS4 (Cas scaffold protein family member 4) Homo sapiens
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Symbol: CASS4
Name: Cas scaffold protein family member 4
Description: Exhibits protein tyrosine kinase binding activity. Involved in positive regulation of cell migration; positive regulation of protein tyrosine kinase activity; and positive regulation of substrate adhesion-dependent cell spreading. Localizes to the focal adhesion. Predicted to colocalize with the plasma membrane; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; benzo[e]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C20orf32; cas scaffolding protein family member 4; CAS4; HEF-like protein; HEF1-EFS-p130Cas-like protein; HEFL; HEPL
Orthologs:
Mus musculus (house mouse) : Cass4 (Cas scaffolding protein family member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cass4 (Cas scaffold protein family member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cass4 (Cas scaffold protein family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CASS4 (Cas scaffold protein family member 4)
Canis lupus familiaris (dog) : CASS4 (Cas scaffold protein family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cass4 (Cas scaffold protein family member 4)
Sus scrofa (pig) : CASS4 (Cas scaffold protein family member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382056,411,550 - 56,460,382 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372054,987,168 - 55,034,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,420,771 - 54,467,243 (+)NCBINCBI36hg18NCBI36
Build 342054,420,770 - 54,467,243NCBI
Celera2051,727,599 - 51,774,824 (+)NCBI
Cytogenetic Map20q13.31NCBI
HuRef2051,772,068 - 51,819,214 (+)NCBIHuRef
CHM1_12054,888,283 - 54,935,521 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CASS4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321668
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.