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Gene: Rtf1 (RTF1, Paf1/RNA polymerase II complex component) Mus musculus
Symbol: Rtf1
Name: RTF1, Paf1/RNA polymerase II complex component
Description: Predicted to have RNA polymerase II C-terminal domain phosphoserine binding activity and single-stranded DNA binding activity. Involved in several processes, including endodermal cell fate commitment; histone H3-K4 trimethylation; and positive regulation of histone H3-K4 methylation. Localizes to the Cdc73/Paf1 complex and nucleolus. Is expressed in several structures, including brain and retina nuclear layer. Orthologous to human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900005O08Rik; 6530416A09Rik; AI853581; AU043144; AW553985; cbp82; gene trap locus 7; Gtl7; Paf1/RNA polymerase II complex component; RNA polymerase-associated protein RTF1 homolog; Rtf1 Paf1/RNA polymerase II complex component homolog; Rtf1, Paf1/RNA polymerase II complex component, homolog
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm382119,675,068 - 119,735,407 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372119,500,804 - 119,561,143 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,366,509 - 119,426,868 (+)NCBImm8
Celera2120,832,949 - 120,891,714 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rtf1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321685
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.