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Gene: TPR (translocated promoter region, nuclear basket protein) Homo sapiens
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Symbol: TPR
Name: translocated promoter region, nuclear basket protein
Description: Exhibits several functions, including dynein complex binding activity; mitogen-activated protein kinase binding activity; and protein homodimerization activity. Involved in several processes, including nucleocytoplasmic transport; regulation of mitotic nuclear division; and regulation of nucleocytoplasmic transport. Localizes to several cellular components, including the kinetochore; microtubule cytoskeleton; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; nucleoprotein TPR; translocated promoter region (to activated MET oncogene); translocated promoter region protein; tumor potentiating region
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,311,652 - 186,375,253 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371186,280,784 - 186,344,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361184,547,407 - 184,611,080 (-)NCBINCBI36hg18NCBI36
Build 341183,014,615 - 183,076,114NCBI
Celera1159,391,490 - 159,455,165 (-)NCBI
Cytogenetic Map1q31.1NCBI
HuRef1157,515,355 - 157,578,976 (-)NCBIHuRef
CHM1_11187,702,490 - 187,766,196 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TPR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321699
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.