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Gene: ARHGEF3 (Rho guanine nucleotide exchange factor 3) Homo sapiens
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Symbol: ARHGEF3
Name: Rho guanine nucleotide exchange factor 3
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Predicted to be involved in several processes, including Rho protein signal transduction; positive regulation of apoptotic process; and regulation of small GTPase mediated signal transduction. Predicted to localize to the cytosol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 59.8 kDA protein; DKFZp434F2429; exchange factor found in platelets and leukemic and neuronal tissues, XPLN; FLJ98126; GEF3; MGC118905; Rho guanine nucleotide exchange factor (GEF) 3; RhoGEF protein; STA3; XPLN
Orthologs:
Mus musculus (house mouse) : Arhgef3 (Rho guanine nucleotide exchange factor (GEF) 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arhgef3 (Rho guanine nucleotide exchange factor 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arhgef3 (Rho guanine nucleotide exchange factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ARHGEF3 (Rho guanine nucleotide exchange factor 3)
Canis lupus familiaris (dog) : ARHGEF3 (Rho guanine nucleotide exchange factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arhgef3 (Rho guanine nucleotide exchange factor 3)
Sus scrofa (pig) : ARHGEF3 (Rho guanine nucleotide exchange factor 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38356,727,419 - 57,079,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37356,761,446 - 57,113,336 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36356,736,486 - 56,810,993 (-)NCBINCBI36hg18NCBI36
Build 34356,736,485 - 56,810,993NCBI
Celera356,727,164 - 57,078,931 (-)NCBI
Cytogenetic Map3p14.3NCBI
HuRef356,809,905 - 57,161,427 (-)NCBIHuRef
CHM1_1356,712,114 - 57,063,671 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ARHGEF3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321712
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.