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Gene: Smpd4 (sphingomyelin phosphodiesterase 4) Mus musculus
Symbol: Smpd4
Name: sphingomyelin phosphodiesterase 4
Description: Predicted to have sphingomyelin phosphodiesterase D activity. Involved in in utero embryonic development. Localizes to nuclear envelope. Is expressed in cranium; hemolymphoid system; nervous system; respiratory system; and urinary system. Orthologous to human SMPD4 (sphingomyelin phosphodiesterase 4); PARTICIPATES IN sphingolipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4122402O22Rik; mKIAA1418; neutral membrane (neutral sphingomyelinase-3); neutral sphingomyelinase 3; neutral sphingomyelinase III; nSMase-3; nSMase3
Homo sapiens (human) : SMPD4 (sphingomyelin phosphodiesterase 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smpd4 (sphingomyelin phosphodiesterase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smpd4 (sphingomyelin phosphodiesterase 4)
Canis lupus familiaris (dog) : SMPD4 (sphingomyelin phosphodiesterase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smpd4 (sphingomyelin phosphodiesterase 4)
Sus scrofa (pig) : SMPD4 (sphingomyelin phosphodiesterase 4)
Chlorocebus sabaeus (African green monkey) : SMPD4 (sphingomyelin phosphodiesterase 4)
Heterocephalus glaber (naked mole-rat) : Smpd4 (sphingomyelin phosphodiesterase 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1617,619,354 - 17,644,828 (+)EnsemblGRCm38mm10GRCm38
GRCm381617,619,354 - 17,644,830 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371617,619,447 - 17,644,923 (+)NCBIGRCm37mm9NCBIm37
MGSCv361617,532,917 - 17,556,946 (+)NCBImm8
Celera1618,192,592 - 18,218,068 (+)NCBICelera
Cytogenetic Map16A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Smpd4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321716
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.