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Gene: Nck1 (non-catalytic region of tyrosine kinase adaptor protein 1) Mus musculus
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Symbol: Nck1
Name: non-catalytic region of tyrosine kinase adaptor protein 1
Description: Exhibits ephrin receptor binding activity; eukaryotic initiation factor eIF2 binding activity; and protein domain specific binding activity. Involved in several processes, including plasma membrane bounded cell projection assembly; positive regulation of cellular component organization; and regulation of response to endoplasmic reticulum stress. Localizes to the cell-cell junction and vesicle membrane. Is expressed in several structures, including extraembryonic component; heart; hemolymphoid system gland; nervous system; and somite. Orthologous to human NCK1 (NCK adaptor protein 1); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6330586M15Rik; cytoplasmic protein NCK1; D230010O13Rik; Nck; NCK adaptor protein 1; Nck-1
Orthologs:
Homo sapiens (human) : NCK1 (NCK adaptor protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nck1 (NCK adaptor protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nck1 (NCK adaptor protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NCK1 (NCK adaptor protein 1)
Canis lupus familiaris (dog) : NCK1 (NCK adaptor protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nck1 (NCK adaptor protein 1)
Sus scrofa (pig) : NCK1 (NCK adaptor protein 1)
Chlorocebus sabaeus (African green monkey) : NCK1 (NCK adaptor protein 1)
Heterocephalus glaber (naked mole-rat) : Nck1 (NCK adaptor protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl9100,492,293 - 100,546,134 (-)Ensembl
GRCm389100,494,302 - 100,546,134 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379100,395,422 - 100,446,472 (-)NCBIGRCm37mm9NCBIm37
MGSCv369100,304,355 - 100,355,405 (-)NCBImm8
Celera9100,033,773 - 100,084,727 (-)NCBICelera
Cytogenetic Map9 E3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nck1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321737
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.