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Gene: Diaph1 (diaphanous related formin 1) Mus musculus
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Symbol: Diaph1
Name: diaphanous related formin 1
Description: Exhibits several functions, including Rho GTPase binding activity; ion channel binding activity; and profilin binding activity. Involved in actin filament polymerization; brain development; and neuron projection development. Localizes to several cellular components, including brush border; neuron projection; and ruffle membrane. Is expressed in several structures, including brain; genitourinary system; gut; liver; and lung. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 1 and sensorineural hearing loss. Orthologous to human DIAPH1 (diaphanous related formin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D18Wsu154e; Dia1; Diap1; diaphanous homolog 1; diaphanous-related formin-1; Drf1; KIAA4062; mDIA1; mKIAA4062; p140mDia; protein diaphanous homolog 1
Orthologs:
Homo sapiens (human) : DIAPH1 (diaphanous related formin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Diaph1 (diaphanous-related formin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Diaph1 (diaphanous related formin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DIAPH1 (diaphanous related formin 1)
Canis lupus familiaris (dog) : DIAPH1 (diaphanous related formin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Diaph1 (diaphanous related formin 1)
Sus scrofa (pig) : DIAPH1 (diaphanous related formin 1)
Chlorocebus sabaeus (African green monkey) : DIAPH1 (diaphanous related formin 1)
Heterocephalus glaber (naked mole-rat) : Diaph1 (diaphanous related formin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1837,843,601 - 37,935,476 (-)EnsemblGRCm38mm10GRCm38
GRCm381837,843,601 - 37,935,622 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371838,004,478 - 38,095,065 (-)NCBIGRCm37mm9NCBIm37
MGSCv361837,970,798 - 38,061,385 (-)NCBImm8
Celera1839,188,303 - 39,278,736 (-)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1819.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Diaph1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321772
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.