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Gene: Pla2g7 (phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)) Mus musculus
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Symbol: Pla2g7
Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Description: Predicted to have 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including plasma lipoprotein particle remodeling; platelet activating factor metabolic process; and positive regulation of monocyte chemotaxis. Predicted to localize to cytoplasm and low-density lipoprotein particle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PLA2G7 (phospholipase A2 group VII); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; LDL-associated phospholipase A2; LDL-PLA(2); PAF 2-acylhydrolase; PAF acetylhydrolase; PAF-AH; platelet-activating factor acetylhydrolase; R75400
Orthologs:
Homo sapiens (human) : PLA2G7 (phospholipase A2 group VII)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pla2g7 (phospholipase A2 group VII)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g7 (phospholipase A2 group VII)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G7 (phospholipase A2 group VII)
Canis lupus familiaris (dog) : PLA2G7 (phospholipase A2 group VII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g7 (phospholipase A2 group VII)
Sus scrofa (pig) : PLA2G7 (phospholipase A2 group VII)
Chlorocebus sabaeus (African green monkey) : PLA2G7 (phospholipase A2 group VII)
Heterocephalus glaber (naked mole-rat) : Pla2g7 (phospholipase A2 group VII)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1743,568,098 - 43,612,201 (+)EnsemblGRCm38mm10GRCm38
GRCm381743,567,994 - 43,612,202 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371743,705,400 - 43,749,150 (+)NCBIGRCm37mm9NCBIm37
MGSCv361743,031,500 - 43,075,242 (+)NCBImm8
Celera1746,991,155 - 47,035,006 (+)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pla2g7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321811
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.