Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pla2g7 (phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)) Mus musculus
Symbol: Pla2g7
Name: phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Description: Predicted to have 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including plasma lipoprotein particle remodeling; platelet activating factor metabolic process; and positive regulation of monocyte chemotaxis. Predicted to localize to cytoplasm and low-density lipoprotein particle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human PLA2G7 (phospholipase A2 group VII); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-alkyl-2-acetylglycerophosphocholine esterase; 2-acetyl-1-alkylglycerophosphocholine esterase; LDL-associated phospholipase A2; LDL-PLA(2); PAF 2-acylhydrolase; PAF acetylhydrolase; PAF-AH; platelet-activating factor acetylhydrolase; R75400
Homo sapiens (human) : PLA2G7 (phospholipase A2 group VII)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pla2g7 (phospholipase A2 group VII)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pla2g7 (phospholipase A2 group VII)
Pan paniscus (bonobo/pygmy chimpanzee) : PLA2G7 (phospholipase A2 group VII)
Canis lupus familiaris (dog) : PLA2G7 (phospholipase A2 group VII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pla2g7 (phospholipase A2 group VII)
Sus scrofa (pig) : PLA2G7 (phospholipase A2 group VII)
Chlorocebus sabaeus (African green monkey) : PLA2G7 (phospholipase A2 group VII)
Heterocephalus glaber (naked mole-rat) : Pla2g7 (phospholipase A2 group VII)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1743,568,098 - 43,612,201 (+)EnsemblGRCm38mm10GRCm38
GRCm381743,567,994 - 43,612,202 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371743,705,400 - 43,749,150 (+)NCBIGRCm37mm9NCBIm37
MGSCv361743,031,500 - 43,075,242 (+)NCBImm8
Celera1746,991,155 - 47,035,006 (+)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pla2g7
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321811
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.