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Gene: DACT2 (dishevelled binding antagonist of beta catenin 2) Homo sapiens
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Symbol: DACT2
Name: dishevelled binding antagonist of beta catenin 2
Description: Predicted to have several functions, including beta-catenin binding activity; delta-catenin binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including epithelial cell morphogenesis; inner medullary collecting duct development; and regulation of signal transduction. Predicted to localize to cytoplasm; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bA503C24.7; C6orf116; dapper antagonist of catenin 2; dapper homolog 2; dapper homolog 2, antagonist of beta-catenin; dapper homolog 2, antagonist of beta-catenin (xenopus); dapper, antagonist of beta-catenin, homolog 2; DAPPER2; dishevelled-binding antagonist of beta-catenin 2; DPR2; FLJ31232; MGC133141; MGC133142; RP11-503C24.7
Orthologs:
Mus musculus (house mouse) : Dact2 (dishevelled-binding antagonist of beta-catenin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dact2 (dishevelled-binding antagonist of beta-catenin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dact2 (dishevelled binding antagonist of beta catenin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DACT2 (dishevelled binding antagonist of beta catenin 2)
Canis lupus familiaris (dog) : DACT2 (dishevelled binding antagonist of beta catenin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dact2 (dishevelled binding antagonist of beta catenin 2)
Sus scrofa (pig) : DACT2 (dishevelled binding antagonist of beta catenin 2)
Chlorocebus sabaeus (African green monkey) : DACT2 (dishevelled binding antagonist of beta catenin 2)
Heterocephalus glaber (naked mole-rat) : Dact2 (dishevelled binding antagonist of beta catenin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl6168,292,830 - 168,319,777 (-)EnsemblGRCh38hg38GRCh38
GRCh386168,292,830 - 168,319,777 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376168,693,510 - 168,720,459 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366168,450,433 - 168,463,251 (-)NCBINCBI36hg18NCBI36
Build 346168,526,141 - 168,538,958NCBI
Celera6169,426,389 - 169,438,204 (-)NCBI
Cytogenetic Map6q27NCBI
HuRef6166,135,772 - 166,147,168 (-)NCBIHuRef
CHM1_16168,956,219 - 168,981,536 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on DACT2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321823
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.