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Gene: NFATC4 (nuclear factor of activated T cells 4) Homo sapiens
Symbol: NFATC4
Name: nuclear factor of activated T cells 4
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of pri-miRNA transcription by RNA polymerase II. Localizes to the cytosol and nuclear speck. Implicated in dilated cardiomyopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NF-AT3; NF-ATc4; NFAT3; nuclear factor of activated T-cells 4; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T cell transcription factor NFAT3; T-cell transcription factor NFAT3
Mus musculus (house mouse) : Nfatc4 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfatc4 (nuclear factor of activated T-cells 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfatc4 (nuclear factor of activated T cells 4)
Pan paniscus (bonobo/pygmy chimpanzee) : NFATC4 (nuclear factor of activated T cells 4)
Canis lupus familiaris (dog) : NFATC4 (nuclear factor of activated T cells 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfatc4 (nuclear factor of activated T cells 4)
Sus scrofa (pig) : NFATC4 (nuclear factor of activated T cells 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1424,365,673 - 24,379,604 (+)Ensembl
GRCh381424,366,911 - 24,379,604 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371424,834,885 - 24,848,810 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,907,094 - 23,918,650 (+)NCBINCBI36hg18NCBI36
Build 341423,907,093 - 23,918,648NCBI
Celera144,700,788 - 4,713,452 (+)NCBI
Cytogenetic Map14q12NCBI
HuRef144,950,950 - 4,963,469 (+)NCBIHuRef
CHM1_11424,834,694 - 24,847,385 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NFATC4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321836
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.