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Gene: Kremen2 (kringle containing transmembrane protein 2) Mus musculus
Symbol: Kremen2
Name: kringle containing transmembrane protein 2
CRRD ID: 1321903
Description: Involved in limb development and negative regulation of ossification. Predicted to localize to integral component of membrane. Is expressed in several structures, including reproductive system; sensory organ; skeletal musculature; skin; and tooth. Orthologous to human KREMEN2 (kringle containing transmembrane protein 2); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH genistein; silicon dioxide; valproic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900054E04Rik; dickkopf receptor 2; kremen protein 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; Krm; Krm2
Homo sapiens (human) : KREMEN2 (kringle containing transmembrane protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kremen2 (kringle containing transmembrane protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kremen2 (kringle containing transmembrane protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KREMEN2 (kringle containing transmembrane protein 2)
Canis lupus familiaris (dog) : KREMEN2 (kringle containing transmembrane protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kremen2 (kringle containing transmembrane protein 2)
Sus scrofa (pig) : KREMEN2 (kringle containing transmembrane protein 2)
Chlorocebus sabaeus (African green monkey) : KREMEN2 (kringle containing transmembrane protein 2)
Heterocephalus glaber (naked mole-rat) : Kremen2 (kringle containing transmembrane protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391723,960,173 - 23,965,305 (-)NCBI
GRCm381723,741,199 - 23,745,960 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,741,197 - 23,745,833 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,878,166 - 23,882,796 (-)NCBIGRCm37mm9NCBIm37
MGSCv361723,468,821 - 23,473,451 (-)NCBImm8
Celera1724,235,074 - 24,239,685 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kremen2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321903
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.