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Gene: DUSP10 (dual specificity phosphatase 10) Homo sapiens
Symbol: DUSP10
Name: dual specificity phosphatase 10
CRRD ID: 1321979
Description: Exhibits phosphoprotein phosphatase activity and protein kinase binding activity. Involved in negative regulation of protein phosphorylation; peptidyl-threonine dephosphorylation; and positive regulation of regulatory T cell differentiation. Localizes to Golgi apparatus; cytosol; and nuclear speck.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dual specificity phosphatase MKP-5; dual specificity protein phosphatase 10; map kinase phosphatase 5; mitogen-activated protein kinase phosphatase 5; MKP-5; MKP5; serine/threonine specific protein phosphatase
Mus musculus (house mouse) : Dusp10 (dual specificity phosphatase 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dusp10 (dual specificity phosphatase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dusp10 (dual specificity phosphatase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : DUSP10 (dual specificity phosphatase 10)
Canis lupus familiaris (dog) : DUSP10 (dual specificity phosphatase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dusp10 (dual specificity phosphatase 10)
Sus scrofa (pig) : DUSP10 (dual specificity phosphatase 10)
Chlorocebus sabaeus (African green monkey) : DUSP10 (dual specificity phosphatase 10)
Heterocephalus glaber (naked mole-rat) : Dusp10 (dual specificity phosphatase 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1221,701,424 - 221,742,089 (-)EnsemblGRCh38hg38GRCh38
GRCh381221,701,424 - 221,742,091 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371221,874,764 - 221,916,204 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361219,941,389 - 219,982,084 (-)NCBINCBI36hg18NCBI36
Celera1195,094,721 - 195,135,415 (-)NCBI
Cytogenetic Map1q41NCBI
HuRef1192,550,111 - 192,590,870 (-)NCBIHuRef
CHM1_11223,147,247 - 223,188,015 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on DUSP10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1321979
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.