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Gene: PAPOLB (poly(A) polymerase beta) Homo sapiens
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Symbol: PAPOLB
Name: poly(A) polymerase beta
Description: Predicted to have polynucleotide adenylyltransferase activity. Predicted to be involved in mRNA polyadenylation. Predicted to localize to the cytoplasm and nucleus; PARTICIPATES IN 3'-end pre-mRNA processing pathway; mRNA decay pathway; INTERACTS WITH copper(II) sulfate; sunitinib; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PAP-beta; PAPT; poly(A) polymerase beta (testis specific); polynucleotide adenylyltransferase beta; testis-specific poly(A) polymerase; TPAP
Orthologs:
Mus musculus (house mouse) : Papolb (poly (A) polymerase beta (testis specific))  MGI  Alliance
Rattus norvegicus (Norway rat) : Papolb (poly(A) polymerase beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Papolb (poly(A) polymerase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : PAPOLB (poly(A) polymerase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Papolb (poly(A) polymerase beta)
Chlorocebus sabaeus (green monkey) : PAPOLB (poly(A) polymerase beta)
Heterocephalus glaber (naked mole-rat) : Papolb (poly(A) polymerase beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl74,857,738 - 4,862,030 (-)Ensembl
GRCh3874,857,738 - 4,862,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3774,897,369 - 4,901,625 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3674,863,895 - 4,868,151 (-)NCBINCBI36hg18NCBI36
Build 3474,670,611 - 4,674,866NCBI
Celera74,856,457 - 4,860,713 (-)NCBI
Cytogenetic Map7p22.1NCBI
HuRef74,812,979 - 4,817,235 (-)NCBIHuRef
CHM1_174,897,092 - 4,901,348 (-)NCBICHM1_1
CRA_TCAGchr7v274,943,724 - 4,947,980 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PAPOLB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322134
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.