Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cradd (CASP2 and RIPK1 domain containing adaptor with death domain) Mus musculus
Analyze
Symbol: Cradd
Name: CASP2 and RIPK1 domain containing adaptor with death domain
Description: Predicted to have death domain binding activity; protease binding activity; and protein binding activity, bridging. Involved in activation of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of apoptotic signaling pathway. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain); PARTICIPATES IN ceramide signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CASP2 and RIPK1 domain-containing adaptor with death domain; caspase and RIP adapter with death domain; death domain-containing protein CRADD; RAIDD; RIP-associated protein with a death domain
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381095,174,739 - 95,324,138 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371094,637,380 - 94,786,731 (-)NCBIGRCm37mm9NCBIm37
MGSCv361094,604,434 - 94,753,785 (-)NCBImm8
Celera1097,149,089 - 97,298,972 (-)NCBICelera
Cytogenetic Map10 C2NCBI
cM Map1049.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cradd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322238
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.