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Gene: Tkfc (triokinase, FMN cyclase) Mus musculus
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Symbol: Tkfc
Name: triokinase, FMN cyclase
Description: Exhibits triokinase activity. Predicted to be involved in carbohydrate phosphorylation; glycerol catabolic process; and negative regulation of MDA-5 signaling pathway. Predicted to localize to the cytosol. Orthologous to human TKFC (triokinase and FMN cyclase); PARTICIPATES IN Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BC021917; bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); Dak; dihydroxyacetone kinase 2 homolog; MGC28742; triokinase/FMN cyclase
Orthologs:
Homo sapiens (human) : TKFC (triokinase and FMN cyclase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tkfc (triokinase and FMN cyclase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tkfc (triokinase and FMN cyclase)
Pan paniscus (bonobo/pygmy chimpanzee) : TKFC (triokinase and FMN cyclase)
Canis lupus familiaris (dog) : TKFC (triokinase and FMN cyclase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tkfc (triokinase and FMN cyclase)
Sus scrofa (pig) : TKFC (triokinase and FMN cyclase)
Chlorocebus sabaeus (African green monkey) : TKFC (triokinase and FMN cyclase)
Heterocephalus glaber (naked mole-rat) : Tkfc (triokinase and FMN cyclase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1910,587,791 - 10,605,654 (-)Ensembl
GRCm381910,592,197 - 10,605,482 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371910,666,687 - 10,678,748 (-)NCBIGRCm37mm9NCBIm37
MGSCv361910,659,242 - 10,671,303 (-)NCBImm8
Celera1911,288,172 - 11,300,234 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Tkfc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322261
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.