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Gene: SRSF10 (serine and arginine rich splicing factor 10) Homo sapiens
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Symbol: SRSF10
Name: serine and arginine rich splicing factor 10
Description: Exhibits RNA binding activity. Involved in mRNA splice site selection and negative regulation of mRNA splicing, via spliceosome. Localizes to nuclear speck. Biomarker of macular degeneration.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 40 kDa SR-repressor protein; DKFZp686H0644; FLJ30749; FLJ43846; FUS interacting protein (serine-arginine rich) 1; FUS-interacting protein (serine-arginine rich) 2; FUS-interacting serine-arginine-rich protein 1; FUSIP1; FUSIP2; neural-salient SR protein; NSSR; PPP1R149; serine-arginine repressor protein (40 kDa); serine/arginine-rich splicing factor 10; SFRS13; SFRS13A; splicing factor SRp38; splicing factor, arginine/serine-rich 13; splicing factor, arginine/serine-rich 13A; SR splicing factor 10; SRp38; SRrp40; TASR; TASR1; TASR2; TLS-associated protein TASR; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein 1; TLS-associated serine-arginine protein 2; TLS-associated SR protein
Orthologs:
Mus musculus (house mouse) : Srsf10 (serine and arginine-rich splicing factor 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Srsf10 (serine and arginine rich splicing factor 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srsf10 (serine and arginine rich splicing factor 10)
Pan paniscus (bonobo/pygmy chimpanzee) : SRSF10 (serine and arginine rich splicing factor 10)
Canis lupus familiaris (dog) : SRSF10 (serine and arginine rich splicing factor 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srsf10 (serine and arginine rich splicing factor 10)
Sus scrofa (pig) : SRSF10 (serine and arginine rich splicing factor 10)
Chlorocebus sabaeus (African green monkey) : SRSF10 (serine and arginine rich splicing factor 10)
Heterocephalus glaber (naked mole-rat) : Srsf10 (serine and arginine rich splicing factor 10)
more info ...
Related Pseudogenes: SRSF10P1   SRSF10P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl123,964,347 - 23,980,927 (-)EnsemblGRCh38hg38GRCh38
GRCh38123,964,347 - 23,980,370 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,292,935 - 24,306,953 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,165,526 - 24,179,408 (-)NCBINCBI36hg18NCBI36
Celera122,623,642 - 22,637,667 (-)NCBI
Cytogenetic Map1p36.11NCBI
HuRef122,546,274 - 22,560,287 (-)NCBIHuRef
CHM1_1124,403,577 - 24,419,683 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SRSF10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322327
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.