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Gene: LGI3 (leucine rich repeat LGI family member 3) Homo sapiens
Symbol: LGI3
Name: leucine rich repeat LGI family member 3
Description: Predicted to have catalytic activity. Predicted to be involved in exocytosis and regulation of exocytosis. Predicted to localize to extracellular region; INTERACTS WITH arsenous acid; diarsenic trioxide; methotrexate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: leucine-rich glioma-inactivated protein 3; leucine-rich repeat LGI family member 3; leucine-rich repeat LGI family, member 3; LGI1-like protein 4; LGIL4
Mus musculus (house mouse) : Lgi3 (leucine-rich repeat LGI family, member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lgi3 (leucine-rich repeat LGI family, member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lgi3 (leucine rich repeat LGI family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LGI3 (leucine rich repeat LGI family member 3)
Canis lupus familiaris (dog) : LGI3 (leucine rich repeat LGI family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lgi3 (leucine rich repeat LGI family member 3)
Sus scrofa (pig) : LGI3 (leucine rich repeat LGI family member 3)
Chlorocebus sabaeus (African green monkey) : LGI3 (leucine rich repeat LGI family member 3)
Heterocephalus glaber (naked mole-rat) : Lgi3 (leucine rich repeat LGI family member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl822,146,830 - 22,157,084 (-)EnsemblGRCh38hg38GRCh38
GRCh38822,146,830 - 22,156,806 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37822,004,343 - 22,014,344 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,060,288 - 22,070,289 (-)NCBINCBI36hg18NCBI36
Build 34822,060,289 - 22,070,289NCBI
Celera820,966,267 - 20,976,328 (-)NCBI
Cytogenetic Map8p21.3NCBI
HuRef820,546,619 - 20,556,646 (-)NCBIHuRef
CHM1_1822,206,009 - 22,216,003 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on LGI3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322345
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.