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Gene: EMX2 (empty spiracles homeobox 2) Homo sapiens
Symbol: EMX2
Name: empty spiracles homeobox 2
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: empty spiracles homolog 2; empty spiracles homolog 2 (drosophila); empty spiracles-like protein 2; homeobox protein EMX2
Mus musculus (house mouse) : Emx2 (empty spiracles homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Emx2 (empty spiracles homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Emx2 (empty spiracles homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EMX2 (empty spiracles homeobox 2)
Canis lupus familiaris (dog) : EMX2 (empty spiracles homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Emx2 (empty spiracles homeobox 2)
Sus scrofa (pig) : EMX2 (empty spiracles homeobox 2)
Chlorocebus sabaeus (African green monkey) : EMX2 (empty spiracles homeobox 2)
Heterocephalus glaber (naked mole-rat) : Emx2 (empty spiracles homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10117,542,445 - 117,549,546 (+)EnsemblGRCh38hg38GRCh38
GRCh3810117,542,445 - 117,549,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710119,301,956 - 119,309,057 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610119,291,946 - 119,299,043 (+)NCBINCBI36hg18NCBI36
Build 3410119,291,945 - 119,299,043NCBI
Celera10113,031,949 - 113,039,046 (+)NCBI
Cytogenetic Map10q26.11NCBI
HuRef10112,930,193 - 112,937,289 (+)NCBIHuRef
CHM1_110119,586,078 - 119,593,194 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on EMX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322367
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.