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Gene: GPR157 (G protein-coupled receptor 157) Homo sapiens
Symbol: GPR157
Name: G protein-coupled receptor 157
Description: Predicted to have G protein-coupled receptor activity. Predicted to be involved in positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway and radial glial cell differentiation. Predicted to localize to the ciliary membrane; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; afimoxifene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ12132; G-protein coupled receptor 157; probable G-protein coupled receptor 157
Mus musculus (house mouse) : Gpr157 (G protein-coupled receptor 157)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gpr157 (G protein-coupled receptor 157)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpr157 (G protein-coupled receptor 157)
Pan paniscus (bonobo/pygmy chimpanzee) : GPR157 (G protein-coupled receptor 157)
Canis lupus familiaris (dog) : GPR157 (G protein-coupled receptor 157)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpr157 (G protein-coupled receptor 157)
Sus scrofa (pig) : GPR157 (G protein-coupled receptor 157)
Chlorocebus sabaeus (African green monkey) : GPR157 (G protein-coupled receptor 157)
Heterocephalus glaber (naked mole-rat) : Gpr157 (G protein-coupled receptor 157)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl19,100,305 - 9,129,102 (-)Ensembl
GRCh3819,100,305 - 9,129,124 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3719,163,472 - 9,189,229 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3619,087,063 - 9,111,816 (-)NCBINCBI36hg18NCBI36
Build 3419,098,741 - 9,123,495NCBI
Celera18,273,844 - 8,298,831 (-)NCBI
Cytogenetic Map1p36.22NCBI
HuRef18,314,669 - 8,339,557 (-)NCBIHuRef
CHM1_119,154,653 - 9,179,610 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on GPR157
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322370
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.