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Gene: CDC14B (cell division cycle 14B) Homo sapiens
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Symbol: CDC14B
Name: cell division cycle 14B
Description: Exhibits protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Involved in positive regulation of ubiquitin protein ligase activity; protein dephosphorylation; and signal transduction involved in G2 DNA damage checkpoint. Localizes to the nucleolus and nucleoplasm. Biomarker of renal cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CDC14 cell division cycle 14 homolog B; Cdc14B1; Cdc14B2; CDC14B3; dual specificity protein phosphatase CDC14B; hCDC14B
Orthologs:
Mus musculus (house mouse) : Cdc14b (CDC14 cell division cycle 14B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc14b (cell division cycle 14B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc14b (cell division cycle 14B)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC14B (cell division cycle 14B)
Canis lupus familiaris (dog) : CDC14B (cell division cycle 14B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc14b (cell division cycle 14B)
Sus scrofa (pig) : CDC14B (cell division cycle 14B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,492,743 - 96,619,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37999,252,807 - 99,382,112 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,302,216 - 98,421,933 (-)NCBINCBI36hg18NCBI36
Build 34996,332,077 - 96,461,667NCBI
Celera969,703,970 - 69,823,685 (-)NCBI
Cytogenetic Map9q22.32-q22.33NCBI
HuRef968,873,293 - 68,940,865 (-)NCBIHuRef
CHM1_1999,409,222 - 99,528,933 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDC14B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322476
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.