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Gene: ZIC2 (Zic family member 2) Homo sapiens
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Symbol: ZIC2
Name: Zic family member 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and chromatin DNA binding activity. Predicted to be involved in central nervous system development; regulation of transcription, DNA-templated; and visual perception. Localizes to the nuclear body. Implicated in holoprosencephaly and holoprosencephaly 5.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HPE5; Zic family member 2 (odd-paired Drosophila homolog); Zic family member 2 (odd-paired homolog, Drosophila); Zinc finger protein of the cerebellum 2; zinc finger protein ZIC 2
Orthologs:
Mus musculus (house mouse) : Zic2 (zinc finger protein of the cerebellum 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zic2 (Zic family member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic2 (Zic family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC2 (Zic family member 2)
Canis lupus familiaris (dog) : ZIC2 (Zic family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic2 (Zic family member 2)
Sus scrofa (pig) : ZIC2 (Zic family member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381399,981,784 - 99,986,765 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3713100,634,026 - 100,639,019 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361399,432,320 - 99,437,020 (+)NCBINCBI36hg18NCBI36
Build 341399,432,319 - 99,437,019NCBI
Celera1381,478,855 - 81,483,555 (+)NCBI
Cytogenetic Map13q32.3NCBI
HuRef1381,227,505 - 81,232,531 (+)NCBIHuRef
CHM1_113100,603,892 - 100,608,865 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ZIC2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322491
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.