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Gene: Sox9 (SRY (sex determining region Y)-box 9) Mus musculus
Symbol: Sox9
Name: SRY (sex determining region Y)-box 9
CRRD ID: 1322514
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; beta-catenin binding activity; and nucleic acid binding activity. Involved in several processes, including animal organ development; negative regulation of cell differentiation; and regulation of animal organ morphogenesis. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study campomelic dysplasia. Human ortholog(s) of this gene implicated in 46,XX sex reversal 2; 46,XY sex reversal 10; and campomelic dysplasia. Orthologous to human SOX9 (SRY-box transcription factor 9); INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010306G03Rik; AV220920; KIAA4243; mKIAA4243; mSox9; SRY-box containing gene 9; transcription factor SOX-9
Homo sapiens (human) : SOX9 (SRY-box transcription factor 9)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sox9 (SRY-box transcription factor 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox9 (SRY-box transcription factor 9)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX9 (SRY-box transcription factor 9)
Canis lupus familiaris (dog) : SOX9 (SRY-box transcription factor 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox9 (SRY-box transcription factor 9)
Sus scrofa (pig) : SOX9 (SRY-box transcription factor 9)
Chlorocebus sabaeus (African green monkey) : SOX9 (SRY-box transcription factor 9)
Heterocephalus glaber (naked mole-rat) : Sox9 (SRY-box transcription factor 9)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl11112,782,224 - 112,787,760 (+)EnsemblGRCm38mm10GRCm38
GRCm3811112,782,210 - 112,787,757 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711112,643,524 - 112,649,071 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611112,598,314 - 112,603,839 (+)NCBImm8
Celera11124,540,008 - 124,545,554 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1177.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Sox9
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322514
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-15
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.