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Gene: PELI1 (pellino E3 ubiquitin protein ligase 1) Homo sapiens
Symbol: PELI1
Name: pellino E3 ubiquitin protein ligase 1
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity; INVOLVED IN negative regulation of necroptotic process; proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH Arsenic Poisoning; skin disease; FOUND IN cytosol (inferred); nucleus (inferred); INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686C18116; E3 ubiquitin-protein ligase pellino homolog 1; MGC50990; pellino homolog 1; pellino-1; pellino-related intracellular-signaling molecule; RING-type E3 ubiquitin transferase pellino homolog 1
Mus musculus (house mouse) : Peli1 (pellino 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Peli1 (pellino E3 ubiquitin protein ligase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Peli1 (pellino E3 ubiquitin protein ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PELI1 (pellino E3 ubiquitin protein ligase 1)
Canis lupus familiaris (dog) : PELI1 (pellino E3 ubiquitin protein ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Peli1 (pellino E3 ubiquitin protein ligase 1)
Sus scrofa (pig) : PELI1 (pellino E3 ubiquitin protein ligase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38264,092,652 - 64,144,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37264,319,786 - 64,371,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36264,173,499 - 64,192,987 (-)NCBINCBI36hg18NCBI36
Build 34264,231,645 - 64,251,134NCBI
Celera264,165,044 - 64,216,871 (-)NCBI
Cytogenetic Map2p14NCBI
HuRef264,059,563 - 64,111,396 (-)NCBIHuRef
CHM1_1264,250,026 - 64,301,844 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PELI1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322532
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.