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Gene: PELI1 (pellino E3 ubiquitin protein ligase 1) Homo sapiens
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Symbol: PELI1
Name: pellino E3 ubiquitin protein ligase 1
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity; INVOLVED IN negative regulation of necroptotic process; proteasome-mediated ubiquitin-dependent protein catabolic process; protein K48-linked ubiquitination; PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH Arsenic Poisoning; skin disease; FOUND IN cytosol (inferred); nucleus (inferred); INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686C18116; E3 ubiquitin-protein ligase pellino homolog 1; MGC50990; pellino homolog 1; pellino-1; pellino-related intracellular-signaling molecule; RING-type E3 ubiquitin transferase pellino homolog 1
Orthologs:
Mus musculus (house mouse) : Peli1 (pellino 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Peli1 (pellino E3 ubiquitin protein ligase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Peli1 (pellino E3 ubiquitin protein ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PELI1 (pellino E3 ubiquitin protein ligase 1)
Canis lupus familiaris (dog) : PELI1 (pellino E3 ubiquitin protein ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Peli1 (pellino E3 ubiquitin protein ligase 1)
Sus scrofa (pig) : PELI1 (pellino E3 ubiquitin protein ligase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38264,092,652 - 64,144,421 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37264,319,786 - 64,371,605 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36264,173,499 - 64,192,987 (-)NCBINCBI36hg18NCBI36
Build 34264,231,645 - 64,251,134NCBI
Celera264,165,044 - 64,216,871 (-)NCBI
Cytogenetic Map2p14NCBI
HuRef264,059,563 - 64,111,396 (-)NCBIHuRef
CHM1_1264,250,026 - 64,301,844 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PELI1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322532
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.