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Gene: CHD4 (chromodomain helicase DNA binding protein 4) Homo sapiens
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Symbol: CHD4
Name: chromodomain helicase DNA binding protein 4
Description: Exhibits RNA polymerase II repressing transcription factor binding activity and histone deacetylase binding activity. Contributes to RNA polymerase II distal enhancer sequence-specific DNA binding activity; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and nucleosomal DNA binding activity. Involved in ATP-dependent chromatin remodeling. Localizes to the NuRD complex; centrosome; and cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent helicase CHD4; CHD-4; chromodomain-helicase-DNA-binding protein 4; DKFZp686E06161; Mi-2 autoantigen 218 kDa protein; Mi-2b; Mi2-BETA; SIHIWES
Orthologs:
Mus musculus (house mouse) : Chd4 (chromodomain helicase DNA binding protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chd4 (chromodomain helicase DNA binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chd4 (chromodomain helicase DNA binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CHD4 (chromodomain helicase DNA binding protein 4)
Canis lupus familiaris (dog) : CHD4 (chromodomain helicase DNA binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chd4 (chromodomain helicase DNA binding protein 4)
Sus scrofa (pig) : CHD4 (chromodomain helicase DNA binding protein 4)
Chlorocebus sabaeus (African green monkey) : CHD4 (chromodomain helicase DNA binding protein 4)
Heterocephalus glaber (naked mole-rat) : Chd4 (chromodomain helicase DNA binding protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl126,570,082 - 6,614,524 (-)Ensembl
GRCh38126,570,082 - 6,607,379 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,679,248 - 6,716,551 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,549,509 - 6,586,812 (-)NCBINCBI36hg18NCBI36
Build 34126,549,509 - 6,586,812NCBI
Celera128,296,110 - 8,333,413 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,533,326 - 6,569,829 (-)NCBIHuRef
CHM1_1126,678,251 - 6,715,604 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on CHD4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322684
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.