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Gene: Prpf4 (pre-mRNA processing factor 4) Mus musculus
Symbol: Prpf4
Name: pre-mRNA processing factor 4
Description: Predicted to have U4 snRNA binding activity and U6 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 70. Orthologous to human PRPF4 (pre-mRNA processing factor 4); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 3,4-methylenedioxymethamphetamine; dibutyl phthalate; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1600015H11Rik; AI874830; AW047464; bN189G18.1; expressed sequence AW047464; MGC117717; U4/U6 small nuclear ribonucleoprotein Prp4; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4
Homo sapiens (human) : PRPF4 (pre-mRNA processing factor 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Prpf4 (pre-mRNA processing factor 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prpf4 (pre-mRNA processing factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPF4 (pre-mRNA processing factor 4)
Canis lupus familiaris (dog) : PRPF4 (pre-mRNA processing factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prpf4 (pre-mRNA processing factor 4)
Sus scrofa (pig) : PRPF4 (pre-mRNA processing factor 4)
Chlorocebus sabaeus (African green monkey) : PRPF4 (pre-mRNA processing factor 4)
Heterocephalus glaber (naked mole-rat) : Prpf4 (pre-mRNA processing factor 4)
more info ...
Related Pseudogenes: Gm19003  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl462,408,797 - 62,426,990 (+)EnsemblGRCm38mm10GRCm38
GRCm38462,408,762 - 62,426,990 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37462,069,817 - 62,088,024 (+)NCBIGRCm37mm9NCBIm37
MGSCv36461,895,144 - 61,913,351 (+)NCBImm8
Celera461,078,790 - 61,096,997 (+)NCBICelera
Cytogenetic Map4B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Prpf4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322688
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.