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Gene: Otub1 (OTU domain, ubiquitin aldehyde binding 1) Mus musculus
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Symbol: Otub1
Name: OTU domain, ubiquitin aldehyde binding 1
Description: Predicted to have NEDD8-specific protease activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin binding activity. Predicted to be involved in protein K48-linked deubiquitination. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including endocrine gland; genitourinary system; nervous system; oral epithelium; and sensory organ. Orthologous to human OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI850305; deubiquitinating enzyme OTUB1; OTU domain-containing ubiquitin aldehyde-binding protein 1; otubain 1; otubain-1; ubiquitin thioesterase OTUB1; ubiquitin-specific-processing protease OTUB1
Orthologs:
Homo sapiens (human) : OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Otub1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Otub1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Canis lupus familiaris (dog) : OTUB1 (OTU domain, ubiquitin aldehyde binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Otub1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Sus scrofa (pig) : OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Chlorocebus sabaeus (green monkey) : OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
Heterocephalus glaber (naked mole-rat) : Otub1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl197,198,202 - 7,206,316 (-)Ensembl
GRCm38197,198,206 - 7,206,284 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37197,272,696 - 7,280,774 (-)NCBIGRCm37mm9NCBIm37
MGSCv36197,265,250 - 7,273,328 (-)NCBImm8
Celera196,975,017 - 6,983,084 (-)NCBICelera
Cytogenetic Map19ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
 
More on Otub1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322724
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.