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Gene: PTPN3 (protein tyrosine phosphatase non-receptor type 3) Homo sapiens
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Symbol: PTPN3
Name: protein tyrosine phosphatase non-receptor type 3
Description: Exhibits several functions, including ATPase binding activity; phosphotyrosine residue binding activity; and sodium channel regulator activity. Involved in several processes, including negative regulation of membrane protein ectodomain proteolysis; regulation of membrane depolarization during action potential; and regulation of sodium ion transmembrane transporter activity. Localizes to the cytoplasm and cytoplasmic side of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cytoskeletal-associated protein tyrosine phosphatase; DKFZp686N0569; protein tyrosin phosphatase H1; protein-tyrosine phosphatase H1; PTP-H1; PTPH1; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 3
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389109,375,694 - 109,538,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379112,137,974 - 112,260,593 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369111,180,337 - 111,265,557 (-)NCBINCBI36hg18NCBI36
Build 349109,220,072 - 109,305,289NCBI
Celera982,637,279 - 82,759,899 (-)NCBI
Cytogenetic Map9q31.3NCBI
HuRef981,738,137 - 81,860,645 (-)NCBIHuRef
CHM1_19112,284,708 - 112,407,241 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PTPN3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322781
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.