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Gene: ITGB8 (integrin subunit beta 8) Homo sapiens
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Symbol: ITGB8
Name: integrin subunit beta 8
Description: Exhibits extracellular matrix protein binding activity. Involved in several processes, including positive regulation of angiogenesis; regulation of gene expression; and vasculogenesis. Localizes to the cell surface and integrin alphav-beta8 complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: integrin beta 8; integrin beta-8; integrin, beta 8
Orthologs:
Mus musculus (house mouse) : Itgb8 (integrin beta 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itgb8 (integrin subunit beta 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb8 (integrin subunit beta 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB8 (integrin subunit beta 8)
Canis lupus familiaris (dog) : ITGB8 (integrin subunit beta 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb8 (integrin subunit beta 8)
Sus scrofa (pig) : ITGB8 (integrin subunit beta 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38720,329,819 - 20,415,754 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37720,370,345 - 20,455,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36720,337,250 - 20,421,907 (+)NCBINCBI36hg18NCBI36
Build 34720,143,985 - 20,223,659NCBI
Celera720,354,962 - 20,439,624 (+)NCBI
Cytogenetic Map7p21.1NCBI
HuRef720,258,397 - 20,343,469 (+)NCBIHuRef
CHM1_1720,370,975 - 20,455,655 (+)NCBICHM1_1
CRA_TCAGchr7v2720,422,044 - 20,506,723 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ITGB8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322799
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.