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Gene: Itgb8 (integrin beta 8) Mus musculus
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Symbol: Itgb8
Name: integrin beta 8
Description: Predicted to have extracellular matrix protein binding activity and integrin binding activity. Involved in ganglioside metabolic process and regulation of transforming growth factor beta activation. Localizes to the integrin alphav-beta8 complex. Is expressed in several structures, including axial skeleton; hindlimb phalanx; reproductive system; ventricular layer; and visual system. Orthologous to human ITGB8 (integrin subunit beta 8); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 4832412O06Rik; integrin beta-8
Orthologs:
Homo sapiens (human) : ITGB8 (integrin subunit beta 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Itgb8 (integrin subunit beta 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb8 (integrin subunit beta 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB8 (integrin subunit beta 8)
Canis lupus familiaris (dog) : ITGB8 (integrin subunit beta 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb8 (integrin subunit beta 8)
Sus scrofa (pig) : ITGB8 (integrin subunit beta 8)
Chlorocebus sabaeus (green monkey) : ITGB8 (integrin subunit beta 8)
Heterocephalus glaber (naked mole-rat) : Itgb8 (integrin subunit beta 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12119,158,022 - 119,238,802 (-)Ensembl
GRCm3812119,162,803 - 119,238,276 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712120,401,276 - 120,476,749 (-)NCBIGRCm37mm9NCBIm37
MGSCv3612113,383,602 - 113,464,521 (-)NCBImm8
MGSCv3612119,602,124 - 119,682,903 (-)NCBImm8
Cytogenetic Map12 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Itgb8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322800
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.