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Gene: FIG4 (FIG4 phosphoinositide 5-phosphatase) Homo sapiens
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Symbol: FIG4
Name: FIG4 phosphoinositide 5-phosphatase
Description: Predicted to have phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity. Predicted to be involved in phosphatidylinositol biosynthetic process. Localizes to the endosome membrane; intracellular membrane-bounded organelle; and lipid droplet. Implicated in Charcot-Marie-Tooth disease type 4J; Yunis-Varon syndrome; and amyotrophic lateral sclerosis type 11.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALS11; BTOP; CMT4J; dJ249I4.1; FIG4 homolog, SAC domain containing lipid phosphatase; FIG4 homolog, SAC1 domain containing lipid phosphatase; FIG4 homolog, SAC1 lipid phosphatase domain containing; hSac3; KIAA0274; phosphatidylinositol 3,5-bisphosphate 5-phosphatase; polyphosphoinositide phosphatase; RP1-249I4.1; Sac domain-containing inositol phosphatase 3; SAC domain-containing protein 3; SAC3; YVS
Orthologs:
Mus musculus (house mouse) : Fig4 (FIG4 phosphoinositide 5-phosphatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fig4 (FIG4 phosphoinositide 5-phosphatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fig4 (FIG4 phosphoinositide 5-phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
Canis lupus familiaris (dog) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fig4 (FIG4 phosphoinositide 5-phosphatase)
Sus scrofa (pig) : FIG4 (FIG4 phosphoinositide 5-phosphatase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl6109,691,312 - 109,825,428 (+)Ensembl
GRCh386109,691,296 - 109,825,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376110,012,424 - 110,146,634 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366110,119,161 - 110,253,327 (+)NCBINCBI36hg18NCBI36
Build 346110,119,160 - 110,253,327NCBI
Celera6110,759,045 - 110,893,292 (+)NCBI
Cytogenetic Map6q21NCBI
HuRef6107,578,606 - 107,713,071 (+)NCBIHuRef
CHM1_16110,275,404 - 110,409,874 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FIG4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322801
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.