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Gene: Rfxank (regulatory factor X-associated ankyrin-containing protein) Mus musculus
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Symbol: Rfxank
Name: regulatory factor X-associated ankyrin-containing protein
CRRD ID: 1322828
Description: Exhibits histone deacetylase binding activity. Involved in Ras protein signal transduction and positive regulation of transcription by RNA polymerase II. Localizes to cytoplasm and nucleus. Is expressed in central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in MHC class II deficiency and severe combined immunodeficiency. Orthologous to human RFXANK (regulatory factor X associated ankyrin containing protein); PARTICIPATES IN antigen processing and presentation pathway; primary immunodeficiency pathway; tuberculosis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ankyrin repeat-containing adapter protein Tvl-1; DNA-binding protein RFXANK; regulatory factor X subunit B; RFX-B; Tv; Tvl1
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl870,130,794 - 70,139,154 (-)EnsemblGRCm38mm10GRCm38
GRCm38870,130,806 - 70,139,197 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37872,654,705 - 72,663,096 (-)NCBIGRCm37mm9NCBIm37
MGSCv36873,059,795 - 73,068,186 (-)NCBImm8
Celera872,686,245 - 72,694,635 (-)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rfxank
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1322828
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.